What is SPRAVATO® (esketamine)?

SPRAVATO® is the brand name for prescription esketamine produced by Janssen Pharmaceutical Companies. SPRAVATO® (esketamine) is a nasal spray form of ketamine that has an on-label use of treating “Adults with treatment-resistant depression (TRD) and/or Depressive symptoms in adults with major depressive disorder (MDD) with suicidal thoughts or actions.

SPRAVATO® (esketamine) for Ketamine Therapy in Mesa, AZ

SPRAVATO® (esketamine) is the form of ketamine used in ketamine therapy at the Arizona Psychedelic Assisted Psychotherapy Institute (AZPAPTI). Our Mesa Arizona ketamine clinic offers therapy sessions for approved patients under the medical supervision of our clinical team.

What is SPRAVATO® / Esketamine Used For?

SPRAVATO® is used to treat depression. It has been shown to be especially helpful in treating cases of depression that involve trauma and traumatic experiences tied to the chronic depression. PTSD and trauma survivors have applauded esketamine for its psychedelic effects — which medicate patients into a semi-sedated state, in-which counseling and therapy sessions become more effective at finding root causes of trauma and depression.

Who Can Prescribe and Administer Ketamine Therapy and SPRAVATO®?

Because of the risk of abuse and possible respiratory depression effects associated with Prescription SPRAVATO®, it is only available to patients who have first met all requirements set-forth by the SPRAVATO® Risk Evaluation and Mitigation Strategy (REMS) Program.

Qualified medical providers and clinics ONLY are allowed to participate in the SPRAVATO® REMS, and in-turn enroll their prospective patients into the program. Our integrated doctors and healthcare team at The Arizona Psychedelic Assisted Psychotherapy Institute (AZPAPTI) are approved to administer SPRAVATO® and other forms of psychedelic therapy to qualified patients in Arizona.

What Are The Side Effects of SPRAVATO® (esketamine)?

• Common Side Effects:
  • Feeling disconnected from yourself, your thoughts, feelings and the things around you | This is the primary effect that ketamine therapy encourages. It is this effect that is said to help patients work through their negative thoughts, feelings and the things around them from a disconnected perspective.
  • Dizziness
  • Nausea
  • Sleepiness
  • Spinning Sensation
  • Decreased Sensitivity and Numbness
  • Anxiety
  • Lethargy / Lack of Energy
  • Increased Blood Pressure and Heart Rate
  • Vomiting
  • Euphoria / Feeling Happy and/or Excited
• Serious Risks and Side Effects
  • Suicidal Thoughts or Feelings*

Esketamine, Ketamine, SPRAVATO® & Suicidal Thoughts and Feelings*

Should I be worried about increased risk of suicide with ketamine therapy and/or the use of SPRAVATO® (esketamine)? No, SPRAVATO® (esketamine)? is considered safe for use by the Food and Drug Administration (FDA) and among many physicians. According to drug maker Janssen, a total of 60 patients (6.0%) experienced at least 1 treatment-emergent adverse event related to suicide.

Of the 3 deaths occurring during clinic trials for SPRAVATO® (esketamine), only 1 was related to suicide, while the other 2 were due to (1) accidental polytrauma and (1) COVID-19 related death.

All Statistics Courtesy of the SPRAVATO® Safety & Tolerability Data Sheet & SPRAVATO® Medication Guide.

Who Should NOT Take SPRAVATO® (esketamine)?

The Arizona Psychedelic Assisted Psychotherapy Institute (AZPAPTI) completes a thorough pre-qualification of all of our patients enrolled in Ketamine Therapy. We check for all points on the SPRAVATO® Risk Evaluation and Mitigation Strategy (REMS) Program checklist, as well as a health background check. SPRAVATO® (esketamine) is not recommended for:

• Those who have had blood vessel disease (aneurysmal vascular) or aneurysm, bursting of blood vessels or a history of blood vessel disorders.
• Those with Arteriovenous Malformations (abnormal connections between veins and arteries).
• Those with a history of bleeding in the brain or hemorrhages.
• Those with a history of heart problems or brain probmes including hypertension.
• Those with a history of stroke or heart attack.
• Those with liver problems.
• Those with a history of psychosis.
• Those who are pregnant or planning to get pregnant.
• Those who are breastfeeding.
• Those who are allergic to ketamine, esketamine, or any of the active or inactive ingredients in SPRAVATO®. (Active ingredient: esketamine hydrochloride  | Inactive ingredients: citric acid monohydrate, edetate disodium, sodium hydroxide, and water for injection)

SPRAVATO® (esketamine) For Depression Treatment

SPRAVATO® (esketamine) is only recommended for those who have NOT had success in traditional forms of depression treatment, including medications with SSRI and/or MAOI Inhibitors or other depression medications. Be sure to let your medical provider know of any medications you are currently taking, or have taken previously for depression.

SPRAVATO® (esketamine) may also be available to patients who have not previously taken anti-depressants, but have attempted unsuccessfully at treating their depression. The Arizona Psychedelic Assisted Psychotherapy Institute (AZPAPTI) completes a thorough pre-qualification of all of our patients and will assist you through this entire process.

Arizona Ketamine Therapy

Learn more about Ketamine Therapy at The Arizona Psychedelic Assisted Psychotherapy Institute (AZPAPTI) with our full resource guide HERE >>

Interested In Qualifying for Ketamine Therapy Sessions?

Start the pre-qualification for ketamine therapy and prescription SPRAVATO® (esketamine). The first step is to contact us to schedule your consultation. Contact Us Now >>